Product Overview
Kisspeptin-10 is a synthetic decapeptide representing the minimal biologically active sequence of the endogenous KISS1 gene product. Operating as a high-affinity ligand for the G-protein-coupled receptor GPR54 (kisspeptin receptor), this compound acts as a primary neuroendocrine gatekeeper, triggering the upstream depolarization of Gonadotropin-Releasing Hormone (GnRH) neurons within reference laboratory models.
In preclinical biomolecular frameworks, Kisspeptin-10 serves as a crucial reference standard to observe hypothalamic signaling pathways, luteinizing hormone (LH) pulse frequency variations, and reproductive axis modulation. Its precise molecular configuration is rigorously monitored via advanced analytical testing to guarantee stable receptor-binding dynamics during in vitro cellular testing.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Profile | Biologically Active KISS1 Decapeptide Fragment |
| Molecular Formula | C₆₃H₇₈N₁₈O₁₃ |
| Molecular Mass | 1303.46 g/mol |
| Sequence | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 |
| Purity Standard | ≥ 98.0% (HPLC & Mass Spectrometry Verified) |
| Physical Format | Sterile, white, lyophilized crystalline powder |
Laboratory Handling & Storage Guidelines
- Reconstitution: Reconstitute using sterile bacteriostatic water or standard laboratory-grade saline solution. Gently swirl the vial in a smooth circular motion; avoid high-shear mechanical agitation to prevent structural denaturation of the fragile decapeptide matrix.
- Long-Term Storage: Store the raw lyophilized powder desiccated at -20°C to -80°C. Protect meticulously from moisture contamination, ambient humidity variations, and direct solar exposure.
- Short-Term Stability: Post-reconstitution, the solution must be stored under stable refrigeration at 2°C to 8°C and utilized within 14 days to preserve maximum biochemical sequence integrity.
⚠️ Regulatory Compliance & Mandatory Disclaimer
IMPORTANT NOTICE: This product is synthesized and distributed exclusively as a pure research chemical for laboratory evaluation, academic investigation, and in vitro experimental models. IT IS STRICTLY NOT FOR HUMAN CONSUMPTION, DIAGNOSTIC, THERAPEUTIC, OR COSMETIC APPLICATIONS. All purchasing entities must represent certified academic or scientific research professionals.
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