PT-141

Product Overview

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analog of the endogenous alpha-melanocyte-stimulating hormone (α-MSH). Developed via targeted structural truncation and cyclization of Melanotan II, PT-141 possesses a distinct neurogenic mechanism of action, operating as a high-affinity agonist at central melanocortin receptors (primarily MC3R and MC4R) within the central nervous system.

In preclinical biomolecular models, PT-141 serves as an essential reference standard to investigate neuroendocrine signaling pathways, copulatory behavior kinetics, and central nervous system-mediated vascular responses. Its unique molecular configuration acts independently of the local vascular system, anchoring it as a vital tool for cellular signaling and in vitro receptor binding assays.

Technical Specifications

Laboratory Handling & Storage Guidelines

• Reconstitution: Reconstitute using sterile bacteriostatic water or standard analytical saline solutions. Gently swirl the vial in a smooth circular motion; avoid aggressive vortexing to preserve optimal cyclic compound architecture.
• Long-Term Storage: Store the raw lyophilized powder desiccated at -20°C to -80°C. Protect meticulously from moisture contamination, ambient atmospheric humidity, and direct solar exposure.
• Short-Term Stability: Post-reconstitution, the matrix solution must be stored under stable refrigeration at 2°C to 8°C and utilized within 14 days to preserve maximum biochemical integrity.

⚠️ Regulatory Compliance & Mandatory Disclaimer

IMPORTANT NOTICE: This product is synthesized and distributed exclusively as a pure research chemical for laboratory evaluation, academic investigation, and in vitro experimental models. IT IS STRICTLY NOT FOR HUMAN CONSUMPTION, DIAGNOSTIC, THERAPEUTIC, OR COSMETIC APPLICATIONS. All purchasing entities must represent certified academic or scientific research professionals.