Product Overview
SS-31 (also known as Elamipretide or Bendavia) is a synthetic, cell-permeable tetrapeptide structured with an alternating aromatic-cationic sequence motif. Operating with high affinity toward mitochondrial inner membranes, this reference compound binds selectively to cardiolipin to inhibit structural degradation and preserve cristae architecture under states of induced oxidative duress.
In preclinical cell-line architectures and biochemical assays, SS-31 serves as an essential scientific standard to explore the modulation of mitochondrial bioenergetics, the reduction of reactive oxygen species (ROS) hyper-production, and the stabilization of adenosine triphosphate (ATP) synthesis networks. Its advanced purity signature is strictly verified via analytical separation matrices to ensure highly consistent kinetics during in vitro evaluations.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Profile | Mitochondrial-Targeted Cardiolipin-Binding Tetrapeptide |
| Molecular Formula | C₃₂H₄₉N₉O₅ |
| Molecular Mass | 639.80 g/mol |
| Sequence | D-Arg-Dmt-Lys-Phe-NH2 (Dmt: 2′,6′-dimethyltyrosine) |
| Purity Standard | ≥ 98.0% (HPLC & Mass Spectrometry Verified) |
| Physical Format | Sterile, white, lyophilized crystalline powder |
Laboratory Handling & Storage Guidelines
- Reconstitution: Reconstitute using sterile deoxygenated laboratory water or standard analytical saline matrices. Gently swirl the vial in a smooth circular motion; avoid high-shear vortexing to protect the baseline structural layout of the tetrapeptide.
- Long-Term Storage: Store the raw lyophilized powder desiccated at -20°C to -80°C. Meticulously isolate the compound from atmospheric humidity, ambient moisture exposure, and direct solar UV kinetics.
- Short-Term Stability: Post-reconstitution, the matrix solution must be stored under stable refrigeration at 2°C to 8°C and utilized within 14 days to preserve maximum biochemical sequence longevity.
⚠️ Regulatory Compliance & Mandatory Disclaimer
IMPORTANT NOTICE: This product is synthesized and distributed exclusively as a pure research chemical for laboratory evaluation, academic investigation, and in vitro experimental models. IT IS STRICTLY NOT FOR HUMAN CONSUMPTION, DIAGNOSTIC, THERAPEUTIC, OR COSMETIC APPLICATIONS. All purchasing entities must represent certified academic or scientific research professionals.
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