Product Overview
Tretiheal Cream 20g (Tretinoin 0.1% w/w) is a potent, first-generation retinoid reference matrix synthesized for advanced in vitro and preclinical cellular studies focusing on retinoic acid receptor (RAR) signaling, extracellular collagen synthesis, and epidermal turnover acceleration. Formulated at a concentrated 0.1% analytical strength, this topical compound allows research cell cultures to evaluate the precise transcriptional activation of target genes regulating extracellular matrix structural integrity and cell division.
Research assays utilizing Tretiheal Cream target the upregulation of Type I collagen gene expression, the inhibition of matrix metalloproteinases (MMPs), and the structural kinetics of stratum corneum cohesion. It functions as an essential scientific standard for investigating retinoid-mediated gene expression, cellular renewal dynamics, and dermal matrix remodeling cascades.
Primary Research Applications
- Acne & Inflammatory Lesion Assays: Evaluates cellular pathways involved in mitigating blackheads, whiteheads, and inflammatory dermal lesions in keratinocyte models.
- Dermal Matrix & Wrinkle Kinetics: Investigates the structural reduction of fine lines and superficial micro-wrinkles to support smoother tissue surface complexions.
- Exfoliation & Epidermal Texture: Tracks accelerated stratum corneum turnover to improve cellular surface texture and address rough facial tissue models.
Technical Specifications
| Parameter / Feature | Specification (Per Research Tube) |
|---|---|
| Active Compound | All-trans-retinoic acid (Tretinoin / Retinoid Agonist) |
| Concentration Ratio | 0.1% w/w (1.0 mg/g active reference standard) |
| CAS Registry Number | 302-79-4 |
| Molecular Formula | C20H28O2 |
| Molar Mass | 300.44 g/mol |
| Purity Grade | ≥ 99.0% Active Analytical Grade (HPLC & Mass Spectrometry Verified) |
| Physical Format | Sterile, smooth, oil-in-water topical cream matrix |
| Unit Net Weight | 20 g per individual aluminum research tube |
Laboratory Handling & Storage Guidelines
- Light Sensitivity Protocols: Dispense strictly under low-actinic or amber ambient laboratory lighting. Tretinoin exhibits high photo-instability and undergoes rapid isomerization under direct UV/visible light kinetics.
- Storage Conditions: Store desiccated in a temperature-regulated environment between 15°C to 25°C (59°F to 77°F). Keep away from radiant heat sources, excessive ambient humidity, and open air exposure.
- Working Aliquots: Reseal primary tubes immediately following micro-sampling to minimize exposure to atmospheric oxygen and prevent premature oxidative breakdown of the active retinoid chain.
⚠️ Regulatory Compliance & Mandatory Disclaimer
IMPORTANT NOTICE: This product is formulated and distributed exclusively as a pure research topical complex for laboratory evaluation, academic investigation, and in vitro experimental models. IT IS STRICTLY NOT FOR HUMAN CONSUMPTION, DIAGNOSTIC, THERAPEUTIC, OR COSMETIC APPLICATIONS. All purchasing entities must represent certified academic or scientific research professionals.
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