Product Overview
Tesamorelin is a stabilized synthetic analogue of Growth Hormone-Releasing Hormone (GHRH). It is structurally composed of the 44 amino acids of human GHRH with an attached trans-3-hexenoic acid group at the N-terminal anchor position. This precision modification enhances its enzymatic resistance against dipeptidyl peptidase-4 (DPP-4) cleavage, ensuring a prolonged physiological profile in cellular assay models compared to unmodified endogenous GHRH configurations.
In reference laboratory studies, Tesamorelin is utilized as a specialized chemical marker to explore lipolytic mechanisms and growth hormone signal transductions. The presence of the lipophilic organic tail maintains distinct pharmacokinetic properties, which are thoroughly verified through advanced standard separation testing metrics before structural designation.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Profile | Stabilized Growth Hormone-Releasing Hormone (GHRH) analogue |
| Molecular Formula | C₂₂₁H₃₆₆N₇₂O₆₇S |
| Molecular Mass | 5135.9 g/mol |
| Sequence | trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 |
| Purity Standard | ≥ 98.0% (HPLC & Mass Spectrometry Verified) |
| Physical Format | Sterile, white, lyophilized crystalline powder |
Laboratory Handling & Storage Guidelines
- Reconstitution: Reconstitute using sterile bacteriostatic water or standard laboratory-grade saline solution. Gently swirl the vial in a smooth circular motion; avoid harsh mechanical agitation to protect the integrity of the fragile polypeptide layout.
- Long-Term Storage: Store the raw lyophilized powder desiccated at -20°C to -80°C. Protect meticulously from moisture contamination, ambient humidity variations, and light exposure.
- Short-Term Stability: Post-reconstitution, the solution must be stored under stable refrigeration at 2°C to 8°C and utilized within 14 days to preserve maximum molecular sequence architecture.
⚠️ Regulatory Compliance & Mandatory Disclaimer
IMPORTANT NOTICE: This product is synthesized and distributed exclusively as a pure research chemical for laboratory evaluation, academic investigation, and *in vitro* experimental models. IT IS STRICTLY NOT FOR HUMAN CONSUMPTION, DIAGNOSTIC, THERAPEUTIC, OR COSMETIC APPLICATIONS. All purchasing entities must represent certified academic or scientific research professionals.
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