GLP-3 (R)

Product Overview

GLP-3 RT (Retatrutide) is a first-in-class, synthetic 39-amino acid single peptide engineered to function as a potent triple hormone receptor agonist. Derived from a modified gastric inhibitory polypeptide (GIP) backbone and conjugated to a C20 fatty di-acid moiety for optimal albumin binding, this compound targets three distinct entero-pancreatic pathways simultaneously: GIPR, GLP-1R, and GCGR (Glucagon).

In biochemical and cell-line evaluation models, GLP-3 RT isolates specific metabolic signaling profiles. While the GIP and GLP-1 receptor activations synergistically modulate glucose-dependent insulin secretion and delay gut motility, the co-activation of the Glucagon receptor actively drives hepatic fat mobilization and enhances cellular energy expenditure dynamics during in vitro testing.

Technical Specifications

Laboratory Handling & Storage Guidelines

• Reconstitution: Reconstitute using sterile bacteriostatic water or standard analytical saline. Mix with a gentle circular motion; avoid high-shear mechanical agitation to preserve the conjugated fatty acid moiety configuration.
• Long-Term Storage: Store the raw lyophilized powder desiccated at -20°C to -80°C. Meticulously protect from atmospheric humidity, ambient moisture, and direct UV radiation.
• Solution Stability: Once reconstituted, store working aliquots strictly at 2°C to 8°C. The solution remains biochemically stable for up to 14 days under constant refrigeration.

⚠️ Regulatory Compliance & Mandatory Disclaimer

IMPORTANT NOTICE: This product is synthesized and distributed exclusively as a pure research chemical for laboratory evaluation, academic investigation, and in vitro experimental models. IT IS STRICTLY NOT FOR HUMAN CONSUMPTION, DIAGNOSTIC, THERAPEUTIC, OR COSMETIC APPLICATIONS. All purchasing entities must represent certified academic or scientific research professionals.