Product Overview
CJC-1295 No DAC (also recognized in laboratory settings as Mod GRF 1-29) is a highly purified synthetic, 29-amino acid tetrasubstituted peptide analogue of Growth Hormone-Releasing Hormone (GHRH). By omitting the Drug Affinity Complex (DAC), this specific compound preserves a highly physiological, pulsatile release profile ideal for acute, time-bound experimental evaluations.
Engineered for structural modification to enhance metabolic stability in vitro, the structure features strategic amino acid substitutions at positions 2, 8, 15, and 27. These precision modifications significantly improve stability against enzymatic degradation by dipeptidyl peptidase-4 (DPP-4), extending the biological half-life relative to endogenous GHRH while avoiding the prolonged, continuous elevation associated with DAC-conjugated formulations.
Technical Specifications
| Parameter | Specification |
|---|---|
| Molecular Formula | C₁₆₅H₂₆₉N₄₇O₄₆ |
| Molecular Mass | 3367.97 g/mol |
| Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 |
| Purity Standard | ≥ 98.0% (HPLC & Mass Spectrometry Verified) |
| Physical Format | Sterile, white, lyophilized crystalline powder |
Laboratory Handling & Storage Guidelines
- Reconstitution: Reconstitute using sterile bacteriostatic water or standard laboratory-grade saline. Gently swirl the vial in a smooth circular motion; do not shake violently to prevent structural shearing of the peptide bonds.
- Long-Term Storage: Store the lyophilized powder desiccated at -20°C to -80°C. Protect completely from direct UV light exposure and ambient moisture.
- Short-Term Stability: Post-reconstitution, the solution must be stored under refrigeration at 2°C to 8°C and utilized within 14 days to preserve maximum integrity.
⚠️ Regulatory Compliance & Mandatory Disclaimer
IMPORTANT NOTICE: This product is synthesized and distributed exclusively as a pure research chemical for laboratory evaluation, academic investigation, and in vitro experimental models. IT IS STRICTLY NOT FOR HUMAN CONSUMPTION, DIAGNOSTIC, THERAPEUTIC, OR COSMETIC APPLICATIONS. All purchasing entities must represent certified academic or scientific research professionals.
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