Product Overview
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring synthetic tripeptide-copper complex. GHK functions as a high-affinity carrier peptide, forming a stable coordination complex with copper (II) ions. This structural organization is widely analyzed in reference laboratories for its capacity to modulate extracellular matrix remodeling and gene expression pathways.
In preclinical biomolecular models, GHK-Cu serves as a targeted standard to observe cellular mechanisms regulating collagen synthesis, fibroblast proliferation, and tissue antioxidant defense pathways. The structural configuration and precise peptide-to-metal ion binding ratio are verified through stringent analytic instrumentation to maintain stable complex behavior during in vitro testing.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | Copper(2+);[(2S)-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanoate] |
| Molecular Formula | C₁₄H₂₂CuN₆O₄ |
| Molecular Mass | 401.91 g/mol |
| Sequence | Gly-His-Lys (Complexed with Copper II) |
| Purity Standard | ≥ 98.0% (HPLC & Mass Spectrometry Verified) |
| Physical Format | Sterile, fine blue crystalline lyophilized powder |
Laboratory Handling & Storage Guidelines
- Reconstitution: Reconstitute using sterile bacteriostatic water or standard laboratory-grade saline solution. Gently swirl the vial in a smooth circular motion; avoid harsh mechanical shaking to prevent structural separation of the copper complex.
- Long-Term Storage: Store the raw lyophilized powder desiccated at -20°C to -80°C. Meticulously protect from ambient moisture, humidity, and direct UV light exposure.
- Short-Term Stability: Post-reconstitution, the solution must be stored under stable refrigeration at 2°C to 8°C and utilized within 14 days to preserve maximum molecular integrity.
⚠️ Regulatory Compliance & Mandatory Disclaimer
IMPORTANT NOTICE: This product is synthesized and distributed exclusively as a pure research chemical for laboratory evaluation, academic investigation, and in vitro experimental models. IT IS STRICTLY NOT FOR HUMAN CONSUMPTION, DIAGNOSTIC, THERAPEUTIC, OR COSMETIC APPLICATIONS. All purchasing entities must represent certified academic or scientific research professionals.
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