Product Overview
KPV (Lysine-Proline-Valine) is a highly purified synthetic tripeptide representing the C-terminal fragment of the endogenous Alpha-Melanocyte Stimulating Hormone (α-MSH). In preclinical molecular investigations, this specific sequence isolates the strong structural anti-inflammatory and cellular signaling modulations of the parent hormone while remaining entirely distinct from melanogenesis or skin pigmentation activation pathways.
Operating dynamically within biochemical cell cultures, KPV serves as a targeted reference standard to observe the inhibition of NF-κB transcription factors and down-stream inflammatory cytokine signaling cascades. Its minimized, low-molecular-weight sequence structure ensures highly consistent compound dynamics and broad matrix stability across diverse analytical testing applications.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Profile | C-Terminal α-MSH Mimetic Tripeptide Fragment |
| Molecular Formula | C₁₆H₂₉N₄O₄ |
| Molecular Mass | 341.43 g/mol |
| Sequence | Lys-Pro-Val (Often synthesized with N-terminal Acetylation for increased stability) |
| Purity Standard | ≥ 98.0% (HPLC & Mass Spectrometry Verified) |
| Physical Format | Sterile, white, lyophilized crystalline powder |
Laboratory Handling & Storage Guidelines
- Reconstitution: Reconstitute using sterile bacteriostatic water or standard laboratory-grade saline solutions. Gently swirl the vial in a smooth circular motion; avoid high-shear mechanical mixing or vortexing to preserve optimal molecular matrix behavior.
- Long-Term Storage: Store the raw lyophilized powder desiccated at -20°C to -80°C. Protect meticulously from moisture contamination, ambient humidity variations, and direct solar light exposure.
- Short-Term Stability: Post-reconstitution, the matrix solution must be stored under stable refrigeration at 2°C to 8°C and utilized within 14 days to preserve maximum biochemical integrity.
⚠️ Regulatory Compliance & Mandatory Disclaimer
IMPORTANT NOTICE: This product is synthesized and distributed exclusively as a pure research chemical for laboratory evaluation, academic investigation, and in vitro experimental models. IT IS STRICTLY NOT FOR HUMAN CONSUMPTION, DIAGNOSTIC, THERAPEUTIC, OR COSMETIC APPLICATIONS. All purchasing entities must represent certified academic or scientific research professionals.
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