Product Overview
TB-500 is a synthetic peptide representing the active fragment of the naturally occurring 43-amino acid protein Thymosin Beta-4. Engineered as a highly stable reference standard, this compound is widely utilized in laboratory settings to investigate systemic tissue remodeling cascades, actin sequestration, and cellular migration dynamics.
In preclinical biomolecular frameworks, TB-500 operates by binding to actin monomers, thereby regulating cellular locomotion, angiogenesis, and matrix repair metrics. Its precise sequence alignment is rigorously monitored via advanced analytical separation testing to guarantee repeatable structural stability and optimal binding kinetics during in vitro cell culture evaluations.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Profile | Synthetic Thymosin Beta-4 Acetylated Fragment |
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular Mass | 4963.5 g/mol |
| Sequence | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH |
| Purity Standard | ≥ 98.0% (HPLC & Mass Spectrometry Verified) |
| Physical Format | Sterile, white, lyophilized crystalline powder |
Laboratory Handling & Storage Guidelines
- Reconstitution: Reconstitute using sterile bacteriostatic water or standard analytical saline matrices. Gently swirl the vial in a smooth circular motion; avoid high-shear vortexing or mechanical shaking to prevent structural shearing of the long polypeptide chain.
- Long-Term Storage: Store the raw lyophilized powder desiccated at -20°C to -80°C. Protect meticulously from moisture contamination, ambient atmospheric humidity, and direct solar exposure.
- Short-Term Stability: Post-reconstitution, the matrix solution must be stored under stable refrigeration at 2°C to 8°C and utilized within 14 days to preserve maximum biochemical integrity.
⚠️ Regulatory Compliance & Mandatory Disclaimer
IMPORTANT NOTICE: This product is synthesized and distributed exclusively as a pure research chemical for laboratory evaluation, academic investigation, and in vitro experimental models. IT IS STRICTLY NOT FOR HUMAN CONSUMPTION, DIAGNOSTIC, THERAPEUTIC, OR COSMETIC APPLICATIONS. All purchasing entities must represent certified academic or scientific research professionals.
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